human ABR Over-expression AAV

Name
AAV-h-ABR

Cat No
AAV-200136

Availability
4-5 weeks

This is an AAV expressing Human ABR.

AAV-200136

AAV-h-ABR

Ready-to-use AAV expressing Human ABR (active BCR-related). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

CMV (default), or choose from 30 different ubiquitous or cell specific promoter

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

MDB

Description (Vector)

ABR encodes a protein that is similar to the protein encoded by the breakpoint cluster region gene located on chromosome 22. The protein encoded by this gene contains a GTPase-activating protein domain, a domain found in members of the Rho family of GTP-binding proteins. Functional studies in mice determined that this protein plays a role in vestibular morphogenesis. Alternatively spliced transcript variants have been reported for this gene.

Gene ID

Gene Name (Vector)

active BCR-related

Gene Symbol

ABR

HGNC ID

HGNC:81

ORF Size (aa)

2580

ORF Size (bp)

2580 bp

RefSeq ID

NM_001092

RefSeq Synonyms

NM_021962, NM_001322842, NM_001322841, NM_001322840, NM_001282149, NM_001256847, NM_001159746, NM_001092, BC172517, BC156483,

Species

human

UniGene ID

Hs.159306

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.