human ABP1 Over-expression AAV

Name
AAV-h-ABP1

Cat No
AAV-200134

Availability
4-5 weeks

This is an AAV expressing Human AOC1.

AAV-200134

AAV-h-ABP1

Ready-to-use AAV expressing Human AOC1 (amine oxidase, copper containing 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

CMV (default), or choose from 30 different ubiquitous or cell specific promoter

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

ABP; ABP1; DAO; DAO1; KAO

Description (Vector)

ABP1 encodes a membrane glycoprotein that is expressed in many epithelium-rich and/or hematopoietic tissues and oxidatively deaminates putrescine and histamine. The protein may play a role in controlling the level of histamine and/or putrescine in these tissues. It also binds to and is inhibited by amiloride, a diuretic that acts by closing epithelial sodium ion channels.

Gene ID

Gene Name (Vector)

amine oxidase, copper containing 1

Gene Symbol

AOC1

HGNC ID

HGNC:80

ORF Size (aa)

2256

ORF Size (bp)

2256 bp

RefSeq ID

NM_001091

RefSeq Synonyms

NM_001272072, NM_001091, BC014093,

Species

human

UniGene ID

Hs.647097

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.