human ABCE1 Over-expression AAV

Name 
AAV-h-ABCE1
Cat No 
AAV-200090
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human ABCE1.

AAV-200090
AAV-h-ABCE1

Ready-to-use AAV expressing Human ABCE1 (ATP binding cassette subfamily E member 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
ABC38; OABP; RLI; RLI1; RNASEL1; RNASELI; RNS4I
Description (Vector)
ABCE1 is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the OABP subfamily. Alternatively referred to as the RNase L inhibitor, this protein functions to block the activity of ribonuclease L. Activation of ribonuclease L leads to inhibition of protein synthesis in the 2-5A/RNase L system, the central pathway for viral interferon action. Two transcript variants encoding the same protein have been found for this gene.
Gene ID
6059
Gene Name (Vector)
ATP binding cassette subfamily E member 1
Gene Symbol
ABCE1
HGNC ID
HGNC:69
ORF Size (aa)
1800
ORF Size (bp)
1800 bp
RefSeq ID
NM_002940
RefSeq Synonyms
NM_002940, NM_001040876, BC016283,
Species
human
UniGene ID
Hs.12013

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.