human ABCD3 Over-expression AAV
This is an AAV expressing Human ABCD3.
AAV-200088
AAV-h-ABCD3
Ready-to-use AAV expressing Human ABCD3 (ATP binding cassette subfamily D member 3). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
ABC43; CBAS5; PMP70; PXMP1; ZWS2
Description (Vector)
ABCD3 is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ALD subfamily, which is involved in peroxisomal import of fatty acids and/or fatty acyl-CoAs in the organelle. All known peroxisomal ABC transporters are half transporters which require a partner half transporter molecule to form a functional homodimeric or heterodimeric transporter. This peroxisomal membrane protein likely plays an important role in peroxisome biogenesis. Mutations have been associated with some forms of Zellweger syndrome, a heterogeneous group of peroxisome assembly disorders. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
Gene ID
5825
Gene Name (Vector)
ATP binding cassette subfamily D member 3
Gene Symbol
ABCD3
HGNC ID
HGNC:67
ORF Size (aa)
1650
ORF Size (bp)
1650 bp
RefSeq ID
NM_002858
RefSeq Synonyms
NM_002858, NM_001122674, BC068509,
Species
human
UniGene ID
Hs.700576
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.