human AASS Over-expression AAV

Name
AAV-h-AASS

Cat No
AAV-200037

Availability
4-5 weeks

This is an AAV expressing Human AASS.

AAV-200037

AAV-h-AASS

Ready-to-use AAV expressing Human AASS (aminoadipate-semialdehyde synthase). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

CMV (default), or choose from 30 different ubiquitous or cell specific promoter

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

LKR/SDH; LKRSDH; LORSDH

Description (Vector)

AASS encodes a bifunctional enzyme that catalyzes the first two steps in the mammalian lysine degradation pathway. The N-terminal and the C-terminal portions of this enzyme contain lysine-ketoglutarate reductase and saccharopine dehydrogenase activity, respectively, resulting in the conversion of lysine to alpha-aminoadipic semialdehyde. Mutations in this gene are associated with familial hyperlysinemia.

Gene ID

10157

Gene Name (Vector)

aminoadipate-semialdehyde synthase

Gene Symbol

AASS

HGNC ID

HGNC:17366

ORF Size (aa)

2778

ORF Size (bp)

2778 bp

RefSeq ID

NM_005763

RefSeq Synonyms

NM_005763, BC172503, BC156456,

Species

human

UniGene ID

Hs.156738

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.