AAV-CreERT2 (AAV serotype DJ) AAV

Name 
AAVDJ-CreERT2
Cat No 
7115
Availability
Immediate
Categories
AAV, Cre Recombinases, Over-Expression

A mutated form of estrogen ligand-binding domain (ERT2) that binds to synthetic antagonists (such as tamoxifen or its derivative 4-hydroxy-tamoxifen) but not to circulating estrogens was fused to the Cre recombinase (Cre) to create the CreERT2, which requires the presence of tamoxifen for Cre recombinase activity. Therefore it makes possible to induce the recombination in cells with tamoxifen.

The AAV-DJ is a synthetic serotype made from DNA family shuffling of 8 wild type serotypes of AAV, including AAV2, 4, 5, 8, 9, avian, bovine and goat AAV. AAV-DJ outperformed standard AAV serotype 1-8 in cultured cells.

This AAV/DJ virus expresses CreERT2 under a CMV promoter.

7115
AAVDJ-CreERT2

Ready-to-use AAV-CreERT2 (AAV serotype DJ). 7115 AAVDJ-CreERT2 AAV-CreERT2 AAV-DJ-CreERT2 AAV/DJ-CreERT2

$495.00
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Product Details

AAV Serotype
AAV-DJ
AAV ITR
AAV2
Promoter
CMV (ubiquitous)
Storage Buffer
PBS/5% Glycerol
Titer
1x10^13 GC/ml
Viral Backbone
Recombinant AAV
Volume (µL)
20

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.