AAV-Cre-GFP (AAV serotype 8) AAV
This AAV serotype 8 virus (with Capsid from AAV8 and ITR from AAV2) expresses Cre Recombinase (tagged with nuclear localization sequence) and eGFP marker. Each gene expression is driven by its own CMV promoter.
Cre recombinase is a Type I topoisomerase from P1 bacteriophage that catalyzes site-specific recombination of DNA between loxP sites. loxP is a 34 bp DNA sequence at which confers directionality. Cre recombinase is used as a tool to genetically modify genes, such as to delete a segment of DNA flanked by LoxP sites in cultured cells or experimental animals.
7062
AAV8-Cre-GFP
Ready-to-use AAV-Cre-GFP (AAV serotype 8). AAV2/8-Cre-GFP AAV8-Cre-GFP Cre recombinase GFP AAV serotype 8 7062
Related Citations
- Inducible Kiss1 knockdown in the hypothalamic arcuate nucleus suppressed pulsatile secretion of luteinizing hormone in male mice. S MINABE, etc, (2020), Journal of Reproduction and Development
- Silencing the insular-striatal circuit decreases alcohol self-administration and increases sensitivity to alcohol. AA Jaramillo, etc, (2018), Behavioural Brain Research
- Regulation of Cognitive Processing by Hippocampal Cholinergic Tone. Al-Onaizi M, etc, (2016), Cerebral Cortex
- Cholinergic Regulation of hnRNPA2/B1 Translation by M1 Muscarinic Receptors. B Kolisnyk, etc, (2016), Journal of Neuroscience
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.