AAV-Cre (AAV serotype 1) AAV
This AAV serotype 1 virus (with Capsid from AAV1 and ITR from AAV2) expresses Cre Recombinase under the control of a CMV promoter. This Cre contains a nuclear localization signal (NLS).
Cre recombinase is a Type I topoisomerase from P1 bacteriophage that catalyzes site-specific recombination of DNA between loxP sites. loxP is a 34 bp DNA sequence at which confers directionality. Cre recombinase is used as a tool to genetically modify genes, such as to delete a segment of DNA flanked by LoxP sites in cultured cells or experimental animals.
7010
AAV1-Cre
Ready-to-use AAV-Cre (AAV serotype 1). AAV2/1-Cre AAV1-Cre Cre recombinase AAV serotype 1 7010
Related Citations
- Exocyst Complex Member EXOC5 Is Required for Survival of Hair Cells and Spiral Ganglion Neurons and Maintenance of Hearing. B Lee, etc, (2018), Molecular Neurobiology
- The severity of vestibular dysfunction in deafness as a determinant of comorbid hyperactivity or anxiety. Antoine MW, etc, (2017), Journal of NeuronScience
- Re-Establishment of Cortical Motor Output Maps and Spontaneous Functional Recovery via Spared Dorsolaterally Projecting Corticospinal Neurons after Dorsal Column Spinal Cord Injury in Adult Mice. BJ Hilton, etc, (2016), The Journal of Neuroscience
- Pten Deletion Promotes Regrowth of Corticospinal Tract Axons 1 Year after Spinal Cord Injury. K Du, etc, (2015), Journal of Neuroscience
- Phasic, Nonsynaptic GABA-A Receptor-Mediated Inhibition Entrains Thalamocortical Oscillations. Zita Rovó, etc, (2014), Journal of Neuroscience
Recently Viewed Products
Ad-CMV-iCre
Cat No: 1045
Ad-CMV-Caspase 9 (DN)
Cat No: 1044
Ad-CMV-Rb
Cat No: 1043
Ad-CMV-p27
Cat No: 1042
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.