human Survivin shRNA Adenovirus
This is an pre-made gene silencing adenovirus that expresses a shRNA to knockdown human Survivin gene. The shRNA expression is driven by an U6 promoter.
The knockdown of this human gene was validated by western blot in A549 cells.
1861
Ad-h-Survivin-shRNA
Ready-to-use human Survivin shRNA Adenovirus. human Survivin shRNA adenovirus gene knockdown1861
Gene Reference Data
Alternate Names
API4; EPR-1
Description (Vector)
BIRC5 is a member of the inhibitor of apoptosis (IAP) gene family, which encode negative regulatory proteins that prevent apoptotic cell death. IAP family members usually contain multiple baculovirus IAP repeat (BIR) domains, but this gene encodes proteins with only a single BIR domain. The encoded proteins also lack a C-terminus RING finger domain. Gene expression is high during fetal development and in most tumors, yet low in adult tissues. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
Gene ID
332
Gene Name (Vector)
baculoviral IAP repeat containing 5
Gene Symbol
BIRC5
HGNC ID
HGNC:593
ORF Size (aa)
429
ORF Size (bp)
429 bp
RefSeq ID
NM_001168
RefSeq Synonyms
NM_001168, NM_001012271, NM_001012270, BC065497, BC034148, BC008718,
Species
human
UniGene ID
Hs.514527
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.