human CASP6 shRNA Adenovirus

Name 
Ad-h-CASP6-shRNA
Cat No 
1816
Availability
Immediate

This is an pre-made gene silencing adenovirus that expresses a shRNA to knockdown human CASP6 gene. The shRNA expression is driven by an U6 promoter.

The knockdown of this human gene was validated by western blot in A549 cells.

1816
Ad-h-CASP6-shRNA

Ready-to-use human CASP6 shRNA Adenovirus. human CASP6 shRNA adenovirus gene knockdown1816

$995.00
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Product Details

Promoter
U6 ()
Reporter
eGFP
shRNA Knockdown (%)
90
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Titer
1x10^10 PFU/ml
Viral Backbone
Human Adenovirus Type5 (dE1/E3)
Volume (µL)
200

Gene Reference Data

Alternate Names
MCH2
Description (Vector)
CASP6 encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein is processed by caspases 7, 8 and 10, and is thought to function as a downstream enzyme in the caspase activation cascade. Alternative splicing of this gene results in two transcript variants that encode different isoforms.
Gene ID
839
Gene Name (Vector)
caspase 6
Gene Symbol
CASP6
HGNC ID
HGNC:1507
ORF Size (aa)
882
ORF Size (bp)
882 bp
RefSeq ID
NM_001226
RefSeq Synonyms
NM_032992, NM_001226, BC004460, BC000305,
Species
human
UniGene ID
Hs.654616

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.