human AKT2 shRNA Adenovirus

Name 
Ad-h-AKT2-shRNA
Cat No 
1802
Availability
Immediate
Categories
Adenovirus, shRNA-Silencing

This is an pre-made gene silencing adenovirus that expresses a shRNA to knockdown human AKT2 gene. The shRNA expression is driven by an U6 promoter.

The knockdown of this human gene was validated by qPCR in A549 cells.

1802
Ad-h-AKT2-shRNA

Ready-to-use human AKT2 shRNA Adenovirus. human AKT2 shRNA adenovirus gene knockdown1802

$995.00
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Product Details

Promoter
U6 ()
Reporter
eGFP
shRNA Knockdown (%)
85
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Titer
1x10^10 PFU/ml
Viral Backbone
Human Adenovirus Type5 (dE1/E3)
Volume (µL)
200

Gene Reference Data

Alternate Names
HIHGHH; murine thymoma viral (v-akt) homolog-2; PKB beta; PKBB; PKBBETA; PRKBB; protein kinase Akt-2; protein kinase B beta; putative v-akt murine thymoma viral oncoprotein 2; rac protein kinase beta; RAC-BETA; RAC-beta serine/threonine-protein kinase; RAC-PK-beta; v-akt murine thymoma viral oncogene homolog 2
Description (eCommerce)
AKT2 is one of 3 highly homologous serine/threonine kinases which include AKT1, AKT2, and AKT3. AKT2 has been found play an integral role in the insulin signaling pathway and is implicated in cancer development.
Gene ID
208
Gene Name (eCommerce)
AKT serine/threonine kinase 2
Gene Name (Vector)
AKT serine/threonine kinase 2
Gene Symbol
AKT2
HGNC ID
HGNC:392
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1317
ORF Size (bp)
1317 bp
Protein Name (eCommerce)
RAC-beta serine/threonine-protein kinase
RefSeq ID
NM_001626
RefSeq Synonyms
NM_001626, NM_001330511, NM_001243028, NM_001243027, BC120995, BC120994, BC063421,
Research Areas
Apoptosis,B-cell Receptor Signaling,Breast Cancer,Cancer,Cardiac Hypertrophy,Cardiology,Cardiovascular,Cell Cycle,Colorectal Cancer,DNA Damage/Repair,EGFR Signaling,EGFR Signaling in Cancer,EPO Signaling,Estrogen Signaling,Fc Receptor Signaling,FGF Signaling,Gene Expression,Glioma,GPCR Signaling,HGF Signaling,HIF-1 Signaling,Host-Virus Interactions,IGF-1 Signaling,Immunology,Innate Immunity,Insulin Signaling,Interleukin Signaling,JAK-STAT Signaling,JNK Signaling,Kidney Cancer,Kinase/Phosphatase,Leukemia,Lung Cancer,MAPK Signaling,Metabolism/Metabolic Process,Mitochondrion,mTOR Signaling,Neurobiology,NF-kB Signaling,NGF Signaling,PDGF Signaling,PI3K/Akt Signaling,PI3K-AKT Signaling in Cancer,Prolactin Signaling,Prostate Cancer,RANKL-RANK Signaling,SCF-KIT Signaling,Signal Transduction,T-cell Receptor Signaling,TNF Signaling,Toll-like Receptor Signaling,Translational Control,TWEAK Signaling,VEGF Signaling
Research Areas (Faceted)
cancer,cardiovascular,cell_biology,cell_cycle,genetics,immunology,infectious_disease,metabolism,neurobiology,signal_transduction,stem_cell_biology,transcription_translation
Species
human
Target Sentence
AKT2 is one of 3 highly homologous serine/threonine kinases which include AKT1, AKT2, and AKT3. AKT2 has been found play an integral role in the insulin signaling pathway and is implicated in cancer development.
UniGene ID
Hs.631535
UniProt ID (eCommerce)
P31751

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.