Cre Recombinase Adenovirus
Cre Recombinase is a Type I topoisomerase from bacteriophage P1 that catalyzes the site-specific recombination of DNA between loxP sites.
This adenovirus expresses both Cre recombinase and Luciferase. Cre & Luciferase are driven by its own CMV promoter.
Check out this instruction video on using our adenovirus Cre to knockout LoxP flanked gene in primary mouse embryonic fibroblasts (MEF).
1705
Ad-Luc-Cre
Ready-to-use Cre Recombinase Adenovirus. Luciferase Cre Luc 1705
Related Citations
- Adenoviral vectors coated with PAMAM dendrimer conjugates allow CAR independent virus uptake and targeting to the EGF Receptor. Vetter, A. etc, (2013), Mol. Pharmaceutics
- cAMP response element-mediated transcription by activating transcription factor-4 (ATF4) is essential for circadian expression of the Period2 gene. Satoru Koyanagi, etc, (2011), J Biol Chem
- Chemoselective modification of viral proteins bearing metabolically introduced. Banerjee PS, Carrico IS., (2011), Methods Mol Biol
- Treatment of murine fulminant hepatitis with genetically engineered endothelial progenitor cells. Fernandez-Ruiz V, etc, (2011), J Hepatol
- Delayed Recovery of Myocardial Blood Flow After Intracoronary Stem Cell Administration. Gyöngyösi M, etc, (2010), Stem Cell Rev
- Akt2 Overexpression Plays A Critical Role In The Establishment Of Colorectal Cancer Metastasis. Rychahou, PG. etc, (2008), PNAS
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.