CRE-Luc Adenovirus
Expression of the Photinus pyralis (firefly) luciferase gene is controlled by a synthetic promoter that contains direct repeats of the transcription recognition sequences for the consensus sites for cyclic AMP response element (CRE).
When this Luciferase reporter adenovirus and an uncharacterized gene are cotransfected into mammalian cells, the activation of endogenous protein kinases initiated by the cotransfected gene product will result in the activation of corresponding trans-activators which in turn stimulate luciferasae expression.
1672
Ad-CRE-Luc
Ready-to-use CRE-Luc Adenovirus. Ad-CRE-Luc 1672
Related Citations
- Phosphatases control PKA-dependent functional microdomains at the outer mitochondrial membrane. A Burdyga, etc, (2018), PNAS
- Hypo-glycosylated hFSH has greater bioactivity than fully-glycosylated recombinant hFSH in human granulosa cells. C Jiang, etc, (2015), The Journal of Clinical Endocrinology & Metabolism
- Small molecule kaempferol modulates PDX-1 protein expression and subsequently promotes pancreatic ß-cell survival and function via CREB. Zhang YL, etc, (2012), Journal of Nutritional Biochesmitry
- Wisp1, A Pro-Mitogenic, Pro-Survival Factor, Mediates Tumor Necrosis Factor-a (Tnf-a)-Stimulated Cardiac Fibroblast Proliferation But Inhibits Tnf-a-Induced Cardiomyocyte Death. Venkatachalam, K, etc, (2009), J. Biol. Chem
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.