stratifin Adenovirus
1602
Ad-SFN/14-3-3-Sigma
Ready-to-use stratifin Adenovirus. Ad-SFN/14-3-3-Sigma, stratifin, SFN adenovirus 1602
Gene Reference Data
Alternate Names
14-3-3 protein sigma; epithelial cell marker protein 1; Stratifin; YWHAS
Description (eCommerce)
14-3-3 sigma was identified as an epithelial cell marker. It is part of the 14-3-3 family of proteins in which seven isoforms have been identified: beta, zeta, gamma, eta, epsilon, tau, and sigma. 14-3-3 proteins function as adaptors that bind with a number of partners to mediate various signaling pathways. 14-3-3 sigma is also called stratifin or HME1 and appears to function as a tumor suppressor whose expression can be downregulated via methylation. Loss of 14-3-3 sigma expression results in a defective G2/M phase checkpoint and appears to contribute to both epithelial and non-epithelial tumorigenesis.
Gene ID
2810
Gene Name (eCommerce)
stratifin
Gene Name (Vector)
stratifin
Gene Symbol
SFN
HGNC ID
HGNC:10773
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
747
ORF Size (bp)
747 bp
Protein Name (eCommerce)
14-3-3 protein sigma
RefSeq ID
NM_006142
RefSeq Synonyms
NM_006142, BC023552, BC002995, BC001550, BC000995, BC000329,
Research Areas
Apoptosis,Breast Cancer,Cancer,Cardiology,Cardiovascular,CD95/FAS Signaling,Cell Cycle,DNA Damage/Repair,FGF Signaling,FoxO Signaling,Immunology,LKB1 Signaling,MAPK Signaling,mTOR Signaling,NFAT Signaling,p53 Signaling,PDGF Signaling,PI3K/Akt Signaling,Signal Transduction,Transcription Factor/Regulator
Research Areas (Faceted)
cancer,cardiovascular,cell_biology,cell_cycle,genetics,immunology,signal_transduction,transcription_translation
Species
human
Target Sentence
14-3-3 sigma was identified as an epithelial cell marker. It is part of the 14-3-3 family of proteins in which seven isoforms have been identified: beta, zeta, gamma, eta, epsilon, tau, and sigma. 14-3-3 proteins function as adaptors that bind with a number of partners to mediate various signaling pathways. 14-3-3 sigma is also called stratifin or HME1 and appears to function as a tumor suppressor whose expression can be downregulated via methylation. Loss of 14-3-3 sigma expression results in a defective G2/M phase checkpoint and appears to contribute to both epithelial and non-epithelial tumorigenesis.
UniGene ID
Hs.523718
UniProt ID (eCommerce)
P31947
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.