Fas ligand (TNF superfamily, member 6) Adenovirus

Name 
Ad-FasL
Cat No 
1594
Availability
Immediate
Categories
Adenovirus, Over-Expression

Programmed cell death, known as apoptosis, of nonessential cells is necessary for embryogenesis, metamorphosis, tissue turnover and proper development and function of the immune system. Apoptosis causes cytoplasmic condensation, nuclear fragmentation and membrane blebbing. There are several proteins that are responsible for the balance of signals that confer cell death and/or cell survival. Among these are the proteins of the tumor necrosis factor ligand superfamily, which includes FAS (APO-1, CD95), FAS ligand (APO-1L, CD178), TRAIL and TWEAK (APO3L) and the FAS accessory protein FAF1 (FAS-associated protein factor-1).

1594
Ad-FasL

Ready-to-use Fas ligand (TNF superfamily, member 6) Adenovirus. Ad-FasL, “Fas ligand (TNF superfamily, member 6)”, FASL, CD178, CD95L, FASLG, TNFSF6, APT1LG1, FAS Ligand adenovirus 1594

$690.00
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Product Details

Promoter
CMV (ubiquitous)
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Titer
1x10^10 PFU/ml
Viral Backbone
Human Adenovirus Type5 (dE1/E3)
Volume (µL)
200

Gene Reference Data

Alternate Names
ALPS1B; APT1LG1; APTL; CD178; CD95-L; CD95L; FASL; TNFSF6; TNLG1A
Description (Vector)
FASLG is the ligand for FAS. Both are transmembrane proteins. Interaction of FAS with this ligand is critical in triggering apoptosis of some types of cells such as lymphocytes. Defects in this gene may be related to some cases of systemic lupus erythematosus (SLE).
Gene ID
356
Gene Name (Vector)
Fas ligand
Gene Symbol
FASLG
HGNC ID
HGNC:11936
ORF Size (aa)
846
ORF Size (bp)
846 bp
RefSeq ID
NM_000639
RefSeq Synonyms
NM_001302746, NM_000639, BC017502,
Species
human
UniGene ID
Hs.2007

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.