SMT3 suppressor of mif two 3 homolog 3 (yeast) Adenovirus

Name 
Ad-SUMO3
Cat No 
1571
Availability
Immediate
Categories
Adenovirus, Over-Expression

Proteolytic degradation by the ubiquitin (Ub) system is essential for normal cell cycle progression, cellular differentiation and stress responses. Proteins conjugated to Ub are marked for progressive degradation by the 26S proteosome. Additional members of the Ub-like protein family include the small ubiquitin-related modifier (SUMO) proteins SUMO-1, 2 and 3. Sumoylation targets proteins to a variety of cellular processing, including nuclear transport, transcriptional regulation, apoptosis and protein stability. NEDD4 is a Ub protein ligase that interacts with the epithelial Na+ channel (ENaC) to regulate cellular Na+ concentration. Two isoforms, designated NEDD4-1 and NEDD4-2 exist. NEDD8 functions as an important regulatory component of cell proliferation.

1571
Ad-SUMO3

Ready-to-use SMT3 suppressor of mif two 3 homolog 3 (yeast) Adenovirus. Ad-SUMO3, SMT3 suppressor of mif two 3 homolog 3 (yeast), SMT3A, SUMO3, SMT3H1, SUMO-3 adenovirus 1571

$690.00
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Product Details

Promoter
CMV (ubiquitous)
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Titer
1x10^10 PFU/ml
Viral Backbone
Human Adenovirus Type5 (dE1/E3)
Volume (µL)
200

Gene Reference Data

Alternate Names
SMT3A; Smt3B; SMT3H1; SUMO-3
Description (Vector)
SUMO proteins, such as SUMO3, and ubiquitin (see MIM 191339) posttranslationally modify numerous cellular proteins and affect their metabolism and function. However, unlike ubiquitination, which targets proteins for degradation, sumoylation participates in a number of cellular processes, such as nuclear transport, transcriptional regulation, apoptosis, and protein stability (Su and Li, 2002 (PubMed 12383504)).(supplied by OMIM, Mar 2008)
Gene ID
6612
Gene Name (Vector)
small ubiquitin-like modifier 3
Gene Symbol
SUMO3
HGNC ID
HGNC:11124
ORF Size (aa)
312
RefSeq ID
NM_006936
RefSeq Synonyms
NM_006936, NM_001286416, BC008420, BC000036,
Species
human
UniGene ID
Hs.474005

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.