Signal transducer and activator of transcription 3 (acute-phase response factor) Adenovirus

Name 
Ad-STAT3
Cat No 
1564
Availability
Immediate
Categories
Adenovirus, Over-Expression

Stats (signal transducers and activators of transcription) are tyrosine phosphorylated transcription factors activated by JAK family kinases. Various ligands, including interferons and growth factors, induce activation of the JAK kinases, which induce Stat activation. Stat1 and Stat2 are induced by IFN-alpha and form a heterodimer that is part of the ISGF-3 transcription factor complex. Stat3-beta is activated by EGF and IL-6. Stat3-alpha is activated by EGF. Highest expression of Stat4 is observed in the testis and myeloid cells. IL-12 has been identified as an activator of Stat4. Stat5 can be activated by prolactin and by IL-3. Stat6 is involved in IL-4 activated signaling pathways. Stat-1 and Stat-3 bind the serum-inducible element (SIE) and GAS/ISRE elements are also known to be STAT-binding sites.

1564
Ad-STAT3

Ready-to-use Signal transducer and activator of transcription 3 (acute-phase response factor) Adenovirus. Ad-STAT3, Signal transducer and activator of transcription 3 (acute-phase response factor), APRF, STAT3 adenovirus 1564

$475.00
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Product Details

Promoter
CMV (ubiquitous)
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Titer
1x10^10 PFU/ml
Viral Backbone
Human Adenovirus Type5 (dE1/E3)
Volume
200 µL

Related Citations

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.