Mitogen-activated protein kinase 7 Adenovirus
The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is specifically activated by mitogen-activated protein kinase kinase 5 (MAP2K5/MEK5). It is involved in the downstream signaling processes of various receptor molecules including receptor type kinases, and G protein-coupled receptors. In response to extracelluar signals, this kinase translocates to cell nucleus, where it regulates gene expression by phosphorylating, and activating different transcription factors.
1542
Ad-MAPK7
Ready-to-use Mitogen-activated protein kinase 7 Adenovirus. Ad-MAPK7, Mitogen-activated protein kinase 7, ERK4, BMK1, ERK5, MAPK7, PRKM7 adenovirus 1542
Gene Reference Data
Alternate Names
big MAP kinase 1; BMK1; BMK-1; BMK1 kinase; ERK4; ERK5; ERK-5; Extracellular signal-regulated kinase 5; extracellular-signal-regulated kinase 5; MAP kinase 7; MAPK 7; mitogen-activated protein kinase 7; PRKM7
Description (eCommerce)
ERK5 (extracellular signal-regulated kinase 5) is a member of the MAP kinase family. ERK5 is also known as MAPK7 (mitogen-activated protein kinase 7). ERK5 is specifically activated by mitogen-activated protein kinase kinase 5 (MAP2K5/MEK5). It is involved in the downstream signaling processes of various receptor molecules including receptor type kinases, and G protein-coupled receptors [taken from NCBI Entrez Gene (GeneID: 5598)].
Description (Vector)
MAPK7 is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is specifically activated by mitogen-activated protein kinase kinase 5 (MAP2K5/MEK5). It is involved in the downstream signaling processes of various receptor molecules including receptor type kinases, and G protein-coupled receptors. In response to extracelluar signals, this kinase translocates to cell nucleus, where it regulates gene expression by phosphorylating, and activating different transcription factors. Four alternatively spliced transcript variants of this gene encoding two distinct isoforms have been reported.
Gene ID
5598
Gene Name (eCommerce)
mitogen-activated protein kinase 7
Gene Name (Vector)
mitogen-activated protein kinase 7
Gene Symbol
MAPK7
HGNC ID
HGNC:6880
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
2451
ORF Size (bp)
2451 bp
Protein Name (eCommerce)
Mitogen-activated protein kinase 7
RefSeq ID
NM_139034
RefSeq Synonyms
NM_139034, NM_139033, NM_139032, NM_002749, BC030134, BC009963, BC007992, BC007404,
Research Areas
Angiogenesis,Apoptosis,BDNF Signaling,Cancer,Cardiac Hypertrophy,Cardiology,Cardiovascular,Cell Cycle,EGFR Signaling,EPO Signaling,GnRH Signaling,GPCR Signaling,Immunology,Innate Immunity,Insulin Signaling,Interleukin Signaling,JAK-STAT Signaling,Kinase/Phosphatase,MAPK Signaling,MicroRNAs in Cancer,Neurobiology,NGF Signaling,Signal Transduction,T-cell Receptor Signaling,TGF-beta Signaling,Toll-like Receptor Signaling,Transcription Factor/Regulator,VEGF Signaling
Research Areas (Faceted)
cancer,cardiovascular,cell_biology,cell_cycle,developmental_biology,genetics,immunology,neurobiology,signal_transduction,transcription_translation
Species
human
Target Sentence
ERK5 (extracellular signal-regulated kinase 5) is a member of the MAP kinase family. ERK5 is also known as MAPK7 (mitogen-activated protein kinase 7). ERK5 is specifically activated by mitogen-activated protein kinase kinase 5 (MAP2K5/MEK5). It is involved in the downstream signaling processes of various receptor molecules including receptor type kinases, and G protein-coupled receptors [taken from NCBI Entrez Gene (GeneID: 5598)].
UniGene ID
Hs.150136
UniProt ID (eCommerce)
Q13164
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.