peptidylprolyl isomerase A (cyclophilin A) Adenovirus

Name 
Ad-Cyclophilin A
Cat No 
1509
Availability
Immediate
Categories
Adenovirus, Over-Expression

The protein encoded by this gene is a member of the peptidyl-prolyl cis-trans isomerase (PPIase) family. PPIases catalyze the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and accelerate the folding of proteins. This protein is a cyclosporin binding-protein. It may play a role in cyclosporin A-mediated immunosuppression. This protein can interact with several HIV proteins including p55 gag, Vpr, and capsid protein. It has been shown to be necessary for the formation of infectious HIV virions.

1509
Ad-Cyclophilin A

Ready-to-use peptidylprolyl isomerase A (cyclophilin A) Adenovirus. Ad-Cyclophilin A, peptidylprolyl isomerase A (cyclophilin A), CYPA, CYPH, PPIA, Cyclophin A adenovirus 1509

$690.00
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Product Details

Promoter
CMV (ubiquitous)
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Titer
1x10^10 PFU/ml
Viral Backbone
Human Adenovirus Type5 (dE1/E3)
Volume (µL)
200

Gene Reference Data

Alternate Names
CYPA; CYPH; HEL-S-69p
Description (Vector)
PPIA encodes a member of the peptidyl-prolyl cis-trans isomerase (PPIase) family. PPIases catalyze the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and accelerate the folding of proteins. The encoded protein is a cyclosporin binding-protein and may play a role in cyclosporin A-mediated immunosuppression. The protein can also interact with several HIV proteins, including p55 gag, Vpr, and capsid protein, and has been shown to be necessary for the formation of infectious HIV virions. Multiple pseudogenes that map to different chromosomes have been reported.
Gene ID
5478
Gene Name (Vector)
peptidylprolyl isomerase A
Gene Symbol
PPIA
HGNC ID
HGNC:9253
ORF Size (aa)
318
RefSeq ID
NM_021130
RefSeq Synonyms
NM_021130, NM_001300981, BC137058, BC137057, BC106030, BC093076, BC073992, BC013915, BC007104, BC005982, BC005320, BC003026, BC000689,
Species
human
UniGene ID
Hs.598115

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.