G protein-coupled receptor kinase 5 Adenovirus
Category: Adenovirus > Over-Expression
Cat. No: 1493
Availability:
Immediate
Name:
Ad-GRK5
Heterotrimeric G protein-mediated signal transduction is a dynamically regulated process with the intensity of signal decreasing over time despite the continued presence of the agonist. This phenomenon, referred to as agonist-mediated desensitization, involves phosphorylation of the receptor by two classes of enzymes. The first is the second messenger regulated kinases such as cAMP dependent protein kinase A and protein kinase C. The second is the G protein-coupled receptor kinases (GRKs). Six members of the GRK family have been identified to date. These include rhodopsin kinase (GRK 1), two forms of beta-adrenergic receptor kinase (GRK 2 or beta-ARK 1 and GRK 3 or beta-ARK 2), IT-11 (GRK 4), GRK 5 and GRK 6. Phosphorylation of receptors by GRKs appears to be strictly dependent on the receptor being in its agonist-activated state.
$690.00
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Viral Details
- Viral Backbone
- Human Adenovirus Type5 (dE1/E3)
- Promoter
- CMV (ubiquitous)
- Storage Buffer
- DMEM, 2% BSA, 2.5% Glycerol
- Volume
- 200ul
- Titer
- 1x10^10 PFU/ml
Gene Details
- Species
- Human
- Gene Symbol
- GRK5
- Gene ID
- 2869
- Gene Synonyms
- GRK5,GPRK5
- RefSeq#
- BC064506
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Product | Cat No. |
---|---|
Ad-CMV-Luc | 1000 |
Ad-GFP | 1060 |
Ad-CMV-b-Gal | 1080 |
Ad-Null | 1240 |
Ad-CMV-Null | 1300 |
Ad-RFP | 1660 |
Ad-CFP | 1766 |
Ad-mCherry | 1767 |
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