F-box only protein 32 Adenovirus

Name 
Ad-Fbox32
Cat No 
1479
Availability
Immediate

MuRF1 (Muscle specific ring finger protein 1) is a nuclear protein that interacts with SMT3b and the large myofibrillar protein titin. MaFbx (Muscle atrophy F-box protein) recognizes and promotes ubiquitination and degradation of phosphorylated proteins during skeletal muscle atrophy. MaFbx or MuRF1 are resistant to atrophy and are therefore potential drug targets for muscle atrophy treatment. Both genes encode ubiquitin ligases and are muscle specific.

1479
Ad-Fbox32

Ready-to-use F-box only protein 32 Adenovirus. Ad-Fbox32, F-box only protein 32, FBOX32 (Atrogin-1) adenovirus 1479

$690.00
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Product Details

Promoter
CMV (ubiquitous)
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Titer
1x10^10 PFU/ml
Viral Backbone
Human Adenovirus Type5 (dE1/E3)
Volume (µL)
200

Gene Reference Data

Alternate Names
4833442G10Rik; AI430017; ATROGIN1; Gm20361; MAFbx
Description (Vector)
Substrate recognition component of a (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Probably recognizes and binds to phosphorylated target proteins during skeletal muscle atrophy. Recognizes TERF1.
Gene ID
67731
Gene Name (Vector)
F-box protein 32
Gene Symbol
Fbxo32
ORF Size (aa)
1068
RefSeq ID
NM_026346
RefSeq Synonyms
NM_026346, BC027211,
Species
mouse
UniGene ID
Mm.292042

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.