Serum/glucocorticoid regulated kinase 2 Adenovirus

Name 
Ad-SGK2
Cat No 
1466
Availability
Immediate

This gene encodes a serine/threonine protein kinase. Although this gene product is similar to serum- and glucocorticoid-induced protein kinase (SGK), this gene is not induced by serum or glucocorticoids. This gene is induced in response to signals that activate phosphatidylinositol 3-kinase, which is also true for SGK. The AGC family of protein kinases, which includes protein kinases A, G, and C, are activated in response to many extracellular signals and play key roles in regulating diverse cellular processes. AGC family members are activated by the phosphorylation of the T loop of their kinase domain by PDK1 and by phosphorylation of a residue located C-terminal to the kinase domain in the hydrophobic motif. Both Akt1 (also known as protein kinase B or PKB) and the Akt-related kinase, Akt2, are rapidly and specifically activated by diverse ligands such as PDGF, EGF, and basic FGF. A third family member, Akt3 (also designated protein kinase B gamma or thyoma viral proto-oncogene 3), is involved in adipocyte and muscle differentiation, glycogen synthesis, glucose uptake, apoptosis and cellular proliferation upon activation by insulin. A fourth family member, SGK, has a catalytic domain similar to Akt1.

1466
Ad-SGK2

Ready-to-use Serum/glucocorticoid regulated kinase 2 Adenovirus. Ad-SGK2, Serum/glucocorticoid regulated kinase 2, SGK2,H-SGK2,DJ138B7.2 adenovirus 1466

$690.00
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Product Details

Promoter
CMV (ubiquitous)
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Titer
1x10^10 PFU/ml
Viral Backbone
Human Adenovirus Type5 (dE1/E3)
Volume (µL)
200

Gene Reference Data

Alternate Names
dJ138B7.2; H-SGK2
Description (Vector)
SGK2 encodes a serine/threonine protein kinase. Although this gene product is similar to serum- and glucocorticoid-induced protein kinase (SGK), this gene is not induced by serum or glucocorticoids. SGK2 is induced in response to signals that activate phosphatidylinositol 3-kinase, which is also true for SGK. Alternative splicing results in multiple transcript variants.
Gene ID
10110
Gene Name (Vector)
SGK2, serine/threonine kinase 2
Gene Symbol
SGK2
HGNC ID
HGNC:13900
ORF Size (aa)
1104
ORF Size (bp)
1104 bp
RefSeq ID
NM_170693
RefSeq Synonyms
NM_170693, NM_016276, NM_001199264, BC065511, BC014037,
Species
human
UniGene ID
Hs.300863

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.