Tumor necrosis factor (ligand) superfamily, member 10 Adenovirus
Cat. No: 1431
Programmed cell death, known as apoptosis, of nonessential cells is necessary for embryogenesis, metamorphosis, tissue turnover and proper development and function of the immune system. Apoptosis causes cytoplasmic condensation, nuclear fragmentation and membrane blebbing. There are several proteins that are responsible for the balance of signals that confer cell death and/or cell survival. Among these are the proteins of the tumor necrosis factor ligand superfamily, which includes FAS (APO-1, CD95), FAS ligand (APO-1L, CD178), TRAIL and TWEAK (APO3L) and the FAS accessory protein FAF1 (FAS-associated protein factor-1).
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- Viral Backbone
- Human Adenovirus Type5 (dE1/E3)
- CMV (ubiquitous)
- Storage Buffer
- DMEM, 2% BSA, 2.5% Glycerol
- 1x10^10 PFU/ml
- Gene Symbol
- Gene ID
- Gene Synonyms
- TL2, APO2L, TRAIL, APO-2L, TNFSF10
This product is referenced in the following publications:
- Thoudam Debraj Singh, etc (2014). Noninvasive Imaging of Apoptosis Induced by Adenovirus-Mediated Cancer Gene Therapy Using a Caspase-3 Biosensor in Living Subjects. Molecular Imaging.
- Joy X. Jiang (2010). NOX2 plays a key role in stellate cell activation and liver fibrogenesis in vivo. Gastroenterology.
- D Das, etc (2016). Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) activates caspases in human prostate cancer cells through sigma 1 receptor. Biochemical and Biophysical Research Communications.