NK2 transcription factor related, locus 5 (Drosophila) Adenovirus

Name 
Ad-NKX2.5/CSX
Cat No 
1417
Availability
Immediate
Categories
Adenovirus, Over-Expression

The Nkx family of homeobox containing transcription factors are differentially expressed and regulate the production of tissue specific target genes. Some members of the Nkx family include TTF-1 (also designated Nkx-2.1), Nkx-2.2, Nkx-2.5 (also designated cardiac specific homeobox protein CSX), Nkx-2.6, Nkx-3.1, Nkx-3.2, Nkx-6.1 and Nkx-6.2. TTF-1 is primarily observed in adult thyroid and lung. Nkx-2.2 and Nkx-6.1 are required for pancreatic B-cell differentiation, and Nkx-2.5 and Nkx-2.6 are involved in normal cardiac development. Nkx-3.1 is predominantly expressed in developing and adult prostate tissue.

1417
Ad-NKX2.5/CSX

Ready-to-use NK2 transcription factor related, locus 5 (Drosophila) Adenovirus. Ad-NKX2.5/CSX, “NK2 transcription factor related, locus 5 (Drosophila)”, CSX,CSX1,NKX2E,NKX2-5,NKX2.5 adenovirus 1417

$690.00
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Product Details

Promoter
CMV (ubiquitous)
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Titer
1x10^10 PFU/ml
Viral Backbone
Human Adenovirus Type5 (dE1/E3)
Volume
200 µL

Gene Reference Data

Alternate Names
CHNG5; CSX; CSX1; HLHS2; NKX2.5; NKX2E; NKX4-1; VSD3
Description (Vector)
NKX2-5 encodes a homeobox-containing transcription factor. This transcription factor functions in heart formation and development. Mutations in this gene cause atrial septal defect with atrioventricular conduction defect, and also tetralogy of Fallot, which are both heart malformation diseases. Mutations in this gene can also cause congenital hypothyroidism non-goitrous type 5, a non-autoimmune condition. Alternative splicing results in multiple transcript variants.
Gene ID
1482
Gene Name (Vector)
NK2 homeobox 5
Gene Symbol
NKX2-5
HGNC ID
HGNC:2488
ORF Size (aa)
975
ORF Size (bp)
975 bp
RefSeq ID
NM_004387
RefSeq Synonyms
NM_004387, NM_001166176, NM_001166175, BC025711,
Species
human
UniGene ID
Hs.54473

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.