Histone deacetylase 6 Adenovirus
Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class II of the histone deacetylase/acuc/apha family. It contains an internal duplication of two catalytic domains which appear to function independently of each other. This protein possesses histone deacetylase activity and represses transcription.
1403
Ad-HDAC6
Ready-to-use Histone deacetylase 6 Adenovirus. Ad-HDAC6, Histone deacetylase 6, HD6,JM21,HDAC6,KIAA0901 adenovirus 1403
Gene Reference Data
Alternate Names
CPBHM; HD6; histone deacetylase 6; JM21; PPP1R90; protein phosphatase 1, regulatory subunit 90
Description (eCommerce)
Histone deacetylase 6 (HDAC6) is a class II histone deacetylase that catalyzes the deacetylation of lysine residues on the N-terminus of core histones. HDAC6 has also been identified as a cytoplasmic deacetylase that acts on tubulin and HSP90 to influence cell motility. Recently HDAC6 has been found to be involved in the stress response as a component of cytoplasmic stress granules.
Description (Vector)
Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class II of the histone deacetylase/acuc/apha family. It contains an internal duplication of two catalytic domains which appear to function independently of each other. This protein possesses histone deacetylase activity and represses transcription.
Gene ID
10013
Gene Name (eCommerce)
histone deacetylase 6
Gene Name (Vector)
histone deacetylase 6
Gene Symbol
HDAC6
HGNC ID
HGNC:14064
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
3192
ORF Size (bp)
3192 bp
Protein Name (eCommerce)
Histone deacetylase 6
RefSeq ID
NM_006044
RefSeq Synonyms
NM_006044, NM_001321231, NM_001321230, NM_001321229, NM_001321228, NM_001321227, NM_001321226, NM_001321225, BC069243, BC013737, BC005872,
Research Areas
Apoptosis,Autophagy,Cancer,Cell Cycle,Chromatin Remodeling,Epigenetic Regulation of Gene Expression,Histone Modification,Host-Virus Interactions,Kinase/Phosphatase,Neurobiology,Neurodevelopment,Notch Signaling,Protein Folding,Signal Transduction,TGF-beta Signaling,TNF Signaling,Transcription Factor/Regulator,Viral Carcinogenesis,Zinc-finger
Research Areas (Faceted)
cancer,cell_biology,cell_cycle,developmental_biology,genetics,immunology,infectious_disease,neurobiology,signal_transduction,transcription_translation
Species
human
Target Sentence
Histone deacetylase 6 (HDAC6) is a class II histone deacetylase that catalyzes the deacetylation of lysine residues on the N-terminus of core histones. HDAC6 has also been identified as a cytoplasmic deacetylase that acts on tubulin and HSP90 to influence cell motility. Recently HDAC6 has been found to be involved in the stress response as a component of cytoplasmic stress granules.
UniGene ID
Hs.6764
UniProt ID (eCommerce)
Q9UBN7
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.