Retinoblastoma-like 2 (p130) Adenovirus
The retinoblastoma susceptibility protein Rb is a 110 kDa phosphorylated protein. Like p53, Rb p110 is an anti-oncogene that is subject to inactivation by either mutation or by binding to certain DNA tumor virus-encoded proteins. Rb binds to and regulates transcription factors involved in cell cycle regulation, including the E2F family. Two Rb related proteins, p107 and p130, also function to regulate specific members of the E2F transcription factor family. Binding and inactivation of E2F proteins by Rb is regulated by cyclin dependent kinase-mediated phosphorylation.
1396
Ad-p130
Ready-to-use Retinoblastoma-like 2 (p130) Adenovirus. Ad-p130, Retinoblastoma-like 2 (p130), RB2,P130,RBL2 adenovirus 1396
Gene Reference Data
Alternate Names
P130; Rb2
Gene ID
5934
Gene Name (Vector)
RB transcriptional corepressor like 2
Gene Symbol
RBL2
HGNC ID
HGNC:9894
ORF Size (aa)
3420
ORF Size (bp)
3420 bp
RefSeq ID
NM_005611
RefSeq Synonyms
NM_005611, NM_001323611, NM_001323610, NM_001323609, NM_001323608, BC034490,
Species
human
UniGene ID
Hs.513609
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.