Rap guanine nucleotide exchange factor (GEF) 4 Adenovirus

Name 
Ad-EPAC2
Cat No 
1392
Availability
Immediate

Epac (exchange protein directly activated by cAMP; also designated cAMP-GEFI) and Epac2 (also designated cAMP-GEFII) compose a novel family of cyclic AMP activated guanine-nucleotide exchange factors (GEFs). Both Epac and Epac2 contain cAMP-binding motifs and a motif common to Ras superfamily GEFs. Epac and Epac2 both function to activate Rap1, a Ras-like GTPase that is known to suppress the oncogenic transformation of cells by Ras. Epac is ubiquitously expressed, whereas Epac2 is primarily expressed in the brain and adrenal glands.

1392
Ad-EPAC2

Ready-to-use Rap guanine nucleotide exchange factor (GEF) 4 Adenovirus. Ad-RAPGEF4/EPAC2, Rap guanine nucleotide exchange factor (GEF) 4, CGEF2,EPAC2,RAPGEF4,CAMP-GEFII adenovirus 1392

$690.00
Request Volume Pricing or Customization

Product Details

Promoter
CMV (ubiquitous)
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Titer
1x10^10 PFU/ml
Viral Backbone
Human Adenovirus Type5 (dE1/E3)
Volume (µL)
200

Gene Reference Data

Alternate Names
CAMP-GEFII; CGEF2; EPAC; EPAC 2; EPAC2; Nbla00496
Gene ID
11069
Gene Name (Vector)
Rap guanine nucleotide exchange factor 4
Gene Symbol
RAPGEF4
HGNC ID
HGNC:16626
ORF Size (aa)
3036
ORF Size (bp)
3036 bp
RefSeq ID
NM_007023
RefSeq Synonyms
NM_007023, NM_001282901, NM_001282900, NM_001282899, NM_001100397, BC040183, BC024004,
Species
human
UniGene ID
Hs.470646

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.