Nuclear receptor subfamily 4, group A, member 1 Adenovirus
Nur77 (also designated NGFI-B), Nurr1 (Nur-related factor 1) and NOR-1 (neuron-derived orphan receptor 1) constitute the NGFI-B subfamily within the nuclear receptor superfamily. Ligands for these protein have not been identified, and therefore they are designated orphan nuclear receptors. Genes of the NGFI-B subfamily are classified as immediate-early genes, which are induced rapidly, but transiently in response to a variety of stimuli, and they have been implicated in cell proliferation, differentiation and apoptosis.
1376
Ad-Nur77
Ready-to-use Nuclear receptor subfamily 4, group A, member 1 Adenovirus. Ad-Nur77, “Nuclear receptor subfamily 4, group A, member 1”, HMR,N10,TR3,NP10,GFRP1,NAK-1,NGFIB,NR4A1,NUR77,MGC9485 adenovirus 1376
Gene Reference Data
Alternate Names
GFRP1; HMR; N10; NAK-1; NGFIB; NP10; NUR77; TR3
Description (Vector)
NR4A1 encodes a member of the steroid-thyroid hormone-retinoid receptor superfamily. Expression is induced by phytohemagglutinin in human lymphocytes and by serum stimulation of arrested fibroblasts. The encoded protein acts as a nuclear transcription factor. Translocation of the protein from the nucleus to mitochondria induces apoptosis. Multiple transcript variants encoding different isoforms have been found for this gene.
Gene ID
3164
Gene Name (Vector)
nuclear receptor subfamily 4 group A member 1
Gene Symbol
NR4A1
HGNC ID
HGNC:7980
ORF Size (aa)
1797
ORF Size (bp)
1797 bp
RefSeq ID
NM_002135
RefSeq Synonyms
NM_173157, NM_002135, NM_001202234, NM_001202233, BC016147,
Species
human
UniGene ID
Hs.524430
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.