Tumor necrosis factor receptor superfamily, member 10b Adenovirus

Name 
Ad-TRAILR2
Cat No 
1356
Availability
Immediate
Categories
Adenovirus, Over-Expression

The protein encoded by this gene is a member of the TNF-receptor superfamily, and contains an intracelluar death domain. This receptor can be activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL/APO-2L), and transduces apoptosis signal. Studies with FADD-deficient mice suggested that FADD, a death domain containing adaptor protein, is required for the apoptosis mediated by this protein.

1356
Ad-TRAILR2

Ready-to-use Tumor necrosis factor receptor superfamily, member 10b Adenovirus. Ad-TRAILR2, “Tumor necrosis factor receptor superfamily, member 10b”, DR5,KILLER,TRICK2,TRICKB,ZTNFR9,TRAILR2,TRICK2A,TRICK2B,TRAIL-R2,TNFRSF10B,KILLER/DR5 adenovirus 1356

$690.00

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Product Details

Promoter
CMV (ubiquitous)
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Titer
1x10^10 PFU/ml
Viral Backbone
Human Adenovirus Type5 (dE1/E3)
Volume
200 µL

Gene Reference Data

Alternate Names
CD262; DR5; KILLER; KILLER/DR5; TRAIL-R2; TRAILR2; TRICK2; TRICK2A; TRICK2B; TRICKB; ZTNFR9
Description (Vector)
TNFRSF10B is a member of the TNF-receptor superfamily, and contains an intracellular death domain. This receptor can be activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL/APO-2L), and transduces an apoptosis signal. Studies with FADD-deficient mice suggested that FADD, a death domain containing adaptor protein, is required for the apoptosis mediated by this protein. Two transcript variants encoding different isoforms and one non-coding transcript have been found for this gene.
Gene ID
8795
Gene Name (Vector)
TNF receptor superfamily member 10b
Gene Symbol
TNFRSF10B
HGNC ID
HGNC:11905
ORF Size (aa)
1323
ORF Size (bp)
1323 bp
RefSeq ID
NM_003842
RefSeq Synonyms
NM_147187, NM_003842, BC001281,
Species
human
UniGene ID
Hs.521456

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.