Src Adenovirus
Several protein tyrosine kinases (Src, Fyn, Lyn, Yes, Lck, Hck, etc) have been identified within the Src gene family. On the basis of their associations with specific cell surface receptors, Src gene family members play critical roles in various signal transduction pathways.
Src is regulated by tyrosine phosphorylation at two sites with opposite effects. Phosphorylation of Tyr 416 in the activation loop of the kinase domain upregulates the enzyme; Phosphorylation of Tyr 527 in the C-terminal by CSK inhibits the enzyme activity.
This adenovirus has a Src activating and signaling molecule.
1166
Ad-CMV-Src
Ready-to-use Src Adenovirus. 1166
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.