Caspase 9 (dn) Adenovirus
This adenovirus contains a Caspase 9 (C287A mutant).
1044
Ad-CMV-Caspase 9 (DN)
Ready-to-use Caspase 9 (dn) Adenovirus. Dominant negative Caspase 9 mutant adenovirus 1044
Related Citations
- Histone Deacetylase Inhibitors Interact with MDA-7/IL-24 to Kill Primary Human Glioblastoma Cells. Hossein A Hamed, etc, (2013), Molecular Pharmacology
- Adenoviral particles for Bcl-2 and DN-Caspase-9 used for the experiments were obtained from Vector BioLabs. Kochuparambil, ST, etc, (2012), BMC Cancer
- Sorafenib Enhances Pemetrexed Cytotoxicity through an Autophagy-Dependent Mechanism in Cancer Cells. Bareford MD, etc, (2011), Cancer Research
- Inhibition of Multiple Protective Signaling Pathways and Ad. 5/3 Delivery Enhances mda-7/IL-24 Therapy of Malignant Glioma. Hossein A Hamed, (2010), Molecular Therapy
- 17-Allylamino-17-Demethoxygeldanamycin and MEK1/2 Inhibitors Kill GI Tumor Cells via Ca2+-Dependent Suppression of GRP78/BiP and Induction of Ceramide and Reactive Oxygen Species. Teneille Walker, (2010), Mol Cancer Ther
- Cisplatin Enhances Protein Kinase R-Like Endoplasmic Reticulum Kinase- and CD95-Dependent Melanoma Differentiation-Associated Gene-7/Interleukin-24¿Induced Killing in Ovarian Carcinoma Cells. Adly Yacoub, (2009), Molecular Pharmacology
- Bcl-2 Family Inhibitors Enhance Histone Deacetylase Inhibitor And Sorafenib Lethality Via Autophagy And Overcome Blockade Of The Extrinsic Pathway To Facilitate Killing. Martin, AP. etc, (2009), Mol Pharmacol
- Mek1/2 Inhibitors And 17AAG Synergize To Kill Human Gi Tumor Cells In Vitro Via Suppression Of C-Flip-S Levels And Activation Of Cd95. Park MA, etc, (2009), Mol Cancer Ther
- PERK-dependent regulation of ceramide synthase 6 and thioredoxin play a key role in mda-7/IL-24-induced killing of primary human glioblastoma multiforme cells. Adly Yacoub, (2009), Cancer Research
- Regulation Of Gst-Mda-7 Toxicity In Human Glioblastoma Cells By Erbb1, Erk1/2, Pi3k, And Jnk1-3 Pathway Signaling. Yacoub, A., etc., (2008), Molecular Cancer Therapeutics
- Mitogen-Activated Protein Kinase Kinase 1/2 Inhibitors And 17-Allylamino-17-Demethoxygeldanamycin Synergize To Kill Human Gastrointestinal Tumor Cells In Vitro Via Suppression Of C-Flip-S Levels And Activation Of Cd95. Park, M., etc., (2008), Molecular Cancer Therapeutics
- Vorinostat And Sorafenib Increase Er Stress, Autophagy And Apoptosis Via Ceramide-Dependent Cd95 And Perk Activation. Park MA, etc, (2008), Cancer Biol Ther
- Caspase-, cathepsin-, and PERK-dependent regulation of MDA-7/IL-24-induced cell killing in primary human glioma cells. Yacoub, A. etc, (2008), Molecular Cancer Therapeutics
- Vorinostat And Sorafenib Synergistically Kill Tumor Cells Via Flip Suppression And Cd95 Activation. Zhang, G., etc., (2008), Clinical Cancer Research
- Extrinsic Pathway- And Cathepsin-Dependent Induction Of Mitochondrial Dysfunction Are Essential For Synergistic Flavopiridol And Vorinostat Lethality In Breast Cancer Cells. Mitchell, C. etc, (2007), Molecular Cancer Therapeutics
- Human Chorionic Gonadotropin (Hcg) Modulates Prostate Cancer Cell Survival After Irradiation Or Hmg Coa Reductase Inhibitor Treatment. Yacoub, A., etc., (2007), Molecular Pharmacology Fast Forward
- Low-Dose Bbr3610 Toxicity In Colon Cancer Cells Is P53-Independent And Enhanced By Inhibition Of Epidermal Growth Factor Receptor (Erbb1)-Phosphatidyl Inositol 3 Kinase Signaling. Mitchell, C., etc., (2007), Mol Pharmacol
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.