human ABCC4 shRNA silencing AAV

Name 
AAV-h-ABCC4-shRNA
Cat No 
shAAV-200080
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human ABCC4.

shAAV-200080
AAV-h-ABCC4-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human ABCC4 (ATP binding cassette subfamily C member 4). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
80
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
MOAT-B; MOATB; MRP4
Description (Vector)
ABCC4 is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. The specific function of this protein has not yet been determined; however, this protein may play a role in cellular detoxification as a pump for its substrate, organic anions. Alternative splicing results in multiple splice variants encoding different isoforms.
Gene ID
10257
Gene Name (Vector)
ATP binding cassette subfamily C member 4
Gene Symbol
ABCC4
HGNC ID
HGNC:55
ORF Size (aa)
2580
ORF Size (bp)
2580 bp
RefSeq ID
NM_005845
RefSeq Synonyms
NM_005845, NM_001301830, NM_001301829, NM_001105515, BC041560,
Species
human
UniGene ID
Hs.508423

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.