human CPT1A Over-expression AAV

Name 
AAV-h-CPT1A
Cat No 
AAV-205937
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human CPT1A.

AAV-205937
AAV-h-CPT1A

Ready-to-use AAV expressing Human CPT1A (carnitine palmitoyltransferase 1A). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
CPT1; CPT1-L; L-CPT1
Description (Vector)
The mitochondrial oxidation of long-chain fatty acids is initiated by the sequential action of carnitine palmitoyltransferase I (which is located in the outer membrane and is detergent-labile) and carnitine palmitoyltransferase II (which is located in the inner membrane and is detergent-stable), together with a carnitine-acylcarnitine translocase. CPT I is the key enzyme in the carnitine-dependent transport across the mitochondrial inner membrane and its deficiency results in a decreased rate of fatty acid beta-oxidation. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Gene ID
1374
Gene Name (Vector)
carnitine palmitoyltransferase 1A
Gene Symbol
CPT1A
HGNC ID
HGNC:2328
ORF Size (aa)
2271
ORF Size (bp)
2271 bp
RefSeq ID
NM_001876
RefSeq Synonyms
NM_001876, NM_001031847, BC000185,
Species
human
UniGene ID
Hs.503043

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.