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human CPSF7 Over-expression AAV

Name 
AAV-h-CPSF7
Cat No 
AAV-205936
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human CPSF7.

AAV-205936
AAV-h-CPSF7

Ready-to-use AAV expressing Human CPSF7 (cleavage and polyadenylation specific factor 7). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
CFIm59; cleavage and polyadenylation specificity factor 59 kDa subunit; cleavage and polyadenylation specificity factor subunit 7; cleavage factor Im complex 59 kDa subunit; CPSF 59 kDa subunit; pre-mRNA cleavage factor I, 59 kDa subunit; pre-mRNA cleavage factor Im 59 kDa subunit
Description (eCommerce)
CPSF59 is the the 59 kDa subunit of the cleavage factor Im complex (CFIm). The CFIm is a heterodimer composed of a 25 kDa (CPSF5) subunit and either the 59 kDa (CPSF7) or 68 kDa (CPSF6) subunit and is essential to the first step of pre-mRNA 3’-end processing. CPSF59 bears an RNA-recognition motif (RRM).
Gene ID
79869
Gene Name (eCommerce)
cleavage and polyadenylation specific factor 7
Gene Name (Vector)
cleavage and polyadenylation specific factor 7
Gene Symbol
CPSF7
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1416
ORF Size (bp)
1416 bp
Protein Name (eCommerce)
Cleavage and polyadenylation specificity factor subunit 7
RefSeq ID
NM_024811
RefSeq Synonyms
NM_024811, NM_001142565, NM_001136040, BC018135,
Research Areas
Gene Expression,mRNA Processing,mRNA Splicing,RNA Binding,RNA Processing,Spliceosome
Research Areas (Faceted)
genetics,transcription_translation,cell_biology
Species
human
Target Sentence
CPSF59 is the the 59 kDa subunit of the cleavage factor Im complex (CFIm). The CFIm is a heterodimer composed of a 25 kDa (CPSF5) subunit and either the 59 kDa (CPSF7) or 68 kDa (CPSF6) subunit and is essential to the first step of pre-mRNA 3’-end processing. CPSF59 bears an RNA-recognition motif (RRM).
UniGene ID
Hs.444552
UniProt ID (eCommerce)
Q8N684

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.