human CPOX Over-expression AAV

Name
AAV-h-CPOX

Cat No
AAV-205919

Availability
4-5 weeks

This is an AAV expressing Human CPOX.

AAV-205919

AAV-h-CPOX

Ready-to-use AAV expressing Human CPOX (coproporphyrinogen oxidase). Available with optional GFP reporter or cell-specific promoter.

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Vector Designer

Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

CMV (default), or choose from 30 different ubiquitous or cell specific promoter

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

CPO; CPX; HCP

Description (Vector)

CPOX is the sixth enzyme of the heme biosynthetic pathway. The encoded enzyme is soluble and found in the intermembrane space of mitochondria. This enzyme catalyzes the stepwise oxidative decarboxylation of coproporphyrinogen III to protoporphyrinogen IX, a precursor of heme. Defects in this gene are a cause of hereditary coproporphyria (HCP).

Gene ID

1371

Gene Name (Vector)

coproporphyrinogen oxidase

Gene Symbol

CPOX

HGNC ID

HGNC:2321

ORF Size (aa)

1365

ORF Size (bp)

1365 bp

RefSeq ID

NM_000097

RefSeq Synonyms

NM_000097, BC023554, BC023551, BC017210,

Species

human

UniGene ID

Hs.476982

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.