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human COX8A Over-expression AAV

Name 
AAV-h-COX8A
Cat No 
AAV-205862
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human COX8A.

AAV-205862
AAV-h-COX8A

Ready-to-use AAV expressing Human COX8A (cytochrome c oxidase subunit 8A). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
COX; COX8; COX8-2; COX8L; VIII; VIII-L
Description (Vector)
COX8A is the terminal enzyme of the respiratory chain, coupling the transfer of electrons from cytochrome c to molecular oxygen, with the concomitant production of a proton electrochemical gradient across the inner mitochondrial membrane. In addition to 3 mitochondrially encoded subunits, which perform the catalytic function, the eukaryotic enzyme contains nuclear-encoded smaller subunits, ranging in number from 4 in some organisms to 10 in mammals. It has been proposed that nuclear-encoded subunits may be involved in the modulation of the catalytic function. This gene encodes one of the nuclear-encoded subunits.
Gene ID
1351
Gene Name (Vector)
cytochrome c oxidase subunit 8A
Gene Symbol
COX8A
HGNC ID
HGNC:2294
ORF Size (aa)
210
RefSeq ID
NM_004074
RefSeq Synonyms
NM_004074, BC063025,
Species
human
UniGene ID
Hs.433901

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.