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human COX7B Over-expression AAV

Name 
AAV-h-COX7B
Cat No 
AAV-205857
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human COX7B.

AAV-205857
AAV-h-COX7B

Ready-to-use AAV expressing Human COX7B (cytochrome c oxidase subunit 7B). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
APLCC; LSDMCA2
Description (Vector)
Cytochrome c oxidase (COX), the terminal component of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. This component is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may function in the regulation and assembly of the complex. This nuclear gene encodes subunit VIIb, which is highly similar to bovine COX VIIb protein and is found in all tissues. This gene may have several pseudogenes on chromosomes 1, 2, 20 and 22.
Gene ID
1349
Gene Name (Vector)
cytochrome c oxidase subunit 7B
Gene Symbol
COX7B
HGNC ID
HGNC:2291
ORF Size (aa)
243
RefSeq ID
NM_001866
RefSeq Synonyms
NM_001866, BC018386,
Species
human
UniGene ID
Hs.522699

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About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.