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human COX7A2L Over-expression AAV

Name 
AAV-h-COX7A2L
Cat No 
AAV-205855
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human COX7A2L.

AAV-205855
AAV-h-COX7A2L

Ready-to-use AAV expressing Human COX7A2L (cytochrome c oxidase subunit 7A2 like). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
COX7AR; COX7RP; EB1; SIG81
Description (Vector)
Cytochrome c oxidase (COX), the terminal component of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. This component is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may function in the regulation and assembly of the complex. This nuclear gene encodes a protein similar to polypeptides 1 and 2 of subunit VIIa in the C-terminal region, and also highly similar to the mouse Sig81 protein sequence. This gene is expressed in all tissues, and upregulated in a breast cancer cell line after estrogen treatment. It is possible that this gene represents a regulatory subunit of COX and mediates the higher level of energy production in target cells by estrogen.
Gene ID
9167
Gene Name (Vector)
cytochrome c oxidase subunit 7A2 like
Gene Symbol
COX7A2L
HGNC ID
HGNC:2289
ORF Size (aa)
345
RefSeq ID
NM_004718
RefSeq Synonyms
NM_004718, NM_001319040, NM_001319038, NM_001319037, NM_001319036, BC007095, BC005251,
Species
human
UniGene ID
Hs.339639

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.