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human COX5B Over-expression AAV

Name 
AAV-h-COX5B
Cat No 
AAV-205835
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human COX5B.

AAV-205835
AAV-h-COX5B

Ready-to-use AAV expressing Human COX5B (cytochrome c oxidase subunit 5B). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
COXVB; Cytochrome c oxidase polypeptide Vb; cytochrome c oxidase polypeptide VB, mitochondrial; cytochrome c oxidase subunit 5B, mitochondrial; cytochrome c oxidase subunit Vb; epididymis secretory sperm binding protein
Description (eCommerce)
Cytochrome c oxidase subunit 5B (COX5B) is one of the nuclear-coded polypeptide chains of cytochrome c oxidase, the terminal oxidase in mitochondrial electron transport [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/P10606].
Description (Vector)
Cytochrome C oxidase (COX) is the terminal enzyme of the mitochondrial respiratory chain. It is a multi-subunit enzyme complex that couples the transfer of electrons from cytochrome c to molecular oxygen and contributes to a proton electrochemical gradient across the inner mitochondrial membrane. The complex consists of 13 mitochondrial- and nuclear-encoded subunits. The mitochondrially-encoded subunits perform the electron transfer and proton pumping activities. The functions of the nuclear-encoded subunits are unknown but they may play a role in the regulation and assembly of the complex. This gene encodes the nuclear-encoded subunit Vb of the human mitochondrial respiratory chain enzyme.
Gene ID
1329
Gene Name (eCommerce)
cytochrome c oxidase subunit 5B
Gene Name (Vector)
cytochrome c oxidase subunit 5B
Gene Symbol
COX5B
HGNC ID
HGNC:2269
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
390
Protein Name (eCommerce)
Cytochrome c oxidase subunit 5B, mitochondrial
RefSeq ID
NM_001862
RefSeq Synonyms
NM_001862, BC006229,
Research Areas
Alzheimer's Disease,Cardiology,Cardiovascular,Huntington's Disease,Metabolism/Metabolic Process,Mitochondrion,Neurobiology,Neurodegeneration,Parkinson's Disease
Research Areas (Faceted)
neurobiology,cardiovascular,metabolism,cell_biology
Species
human
Target Sentence
Cytochrome c oxidase subunit 5B (COX5B) is one of the nuclear-coded polypeptide chains of cytochrome c oxidase, the terminal oxidase in mitochondrial electron transport [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/P10606].
UniGene ID
Hs.1342
UniProt ID (eCommerce)
P10606

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.