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human COTL1 Over-expression AAV

Name 
AAV-h-COTL1
Cat No 
AAV-205807
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human COTL1.

AAV-205807
AAV-h-COTL1

Ready-to-use AAV expressing Human COTL1 (coactosin like F-actin binding protein 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
CLP
Description (Vector)
COTL1 encodes one of the numerous actin-binding proteins which regulate the actin cytoskeleton. This protein binds F-actin, and also interacts with 5-lipoxygenase, which is the first committed enzyme in leukotriene biosynthesis. Although this gene has been reported to map to chromosome 17 in the Smith-Magenis syndrome region, the best alignments for this gene are to chromosome 16. The Smith-Magenis syndrome region is the site of two related pseudogenes.
Gene ID
23406
Gene Name (Vector)
coactosin like F-actin binding protein 1
Gene Symbol
COTL1
HGNC ID
HGNC:18304
ORF Size (aa)
429
RefSeq ID
NM_021149
RefSeq Synonyms
NM_021149, BC053682, BC042970, BC016702, BC010884, BC010039,
Species
human
UniGene ID
Hs.289092

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About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.