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human COQ2 Over-expression AAV

Name 
AAV-h-COQ2
Cat No 
AAV-205784
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human COQ2.

AAV-205784
AAV-h-COQ2

Ready-to-use AAV expressing Human COQ2 (coenzyme Q2, polyprenyltransferase). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
CL640; COQ10D1; MSA1; PHB:PPT
Description (Vector)
COQ2 encodes an enzyme that functions in the final steps in the biosynthesis of CoQ (ubiquinone), a redox carrier in the mitochondrial respiratory chain and a lipid-soluble antioxidant. This enzyme, which is part of the coenzyme Q10 pathway, catalyzes the prenylation of parahydroxybenzoate with an all-trans polyprenyl group. Mutations in this gene cause coenzyme Q10 deficiency, a mitochondrial encephalomyopathy, and also COQ2 nephropathy, an inherited form of mitochondriopathy with primary renal involvement.
Gene ID
27235
Gene Name (Vector)
coenzyme Q2, polyprenyltransferase
Gene Symbol
COQ2
HGNC ID
HGNC:25223
ORF Size (aa)
1116
ORF Size (bp)
1116 bp
RefSeq ID
NM_015697
RefSeq Synonyms
NM_015697, BC020728, BC008804,
Species
human
UniGene ID
Hs.144304

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.