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human CLEC7A Over-expression AAV

Name 
AAV-h-CLEC7A
Cat No 
AAV-205446
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human CLEC7A.

AAV-205446
AAV-h-CLEC7A

Ready-to-use AAV expressing Human CLEC7A (C-type lectin domain family 7 member A). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
BGR; CANDF4; CD369; CLECSF12; DECTIN1; SCARE2
Description (Vector)
CLEC7A encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. The encoded glycoprotein is a small type II membrane receptor with an extracellular C-type lectin-like domain fold and a cytoplasmic domain with an immunoreceptor tyrosine-based activation motif. It functions as a pattern-recognition receptor that recognizes a variety of beta-1,3-linked and beta-1,6-linked glucans from fungi and plants, and in this way plays a role in innate immune response. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. CLEC7A is closely linked to other CTL/CTLD superfamily members on chromosome 12p13 in the natural killer gene complex region.
Gene ID
64581
Gene Name (Vector)
C-type lectin domain family 7 member A
Gene Symbol
CLEC7A
HGNC ID
HGNC:14558
ORF Size (aa)
399
ORF Size (bp)
399 bp
RefSeq ID
NM_022570
RefSeq Synonyms
NM_197954, NM_197950, NM_197949, NM_197948, NM_197947, NM_022570, BC071746,
Species
human
UniGene ID
Hs.143929

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.