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human CHMP4A Over-expression AAV

Name 
AAV-h-CHMP4A
Cat No 
AAV-205164
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human CHMP4A.

AAV-205164
AAV-h-CHMP4A

Ready-to-use AAV expressing Human CHMP4A (charged multivesicular body protein 4A). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
C14orf123; CHMP4; CHMP4B; HSPC134; SHAX2; SNF7; SNF7-1; VPS32-1; VPS32A
Description (Vector)
CHMP4A belongs to the chromatin-modifying protein/charged multivesicular body protein (CHMP) family. These proteins are components of ESCRT-III (endosomal sorting complex required for transport III), a complex involved in degradation of surface receptor proteins and formation of endocytic multivesicular bodies (MVBs). Some CHMPs have both nuclear and cytoplasmic/vesicular distributions, and one such CHMP, CHMP1A (MIM 164010), is required for both MVB formation and regulation of cell cycle progression (Tsang et al., 2006 (PubMed 16730941)).(supplied by OMIM, Mar 2008)
Gene ID
29082
Gene Name (Vector)
charged multivesicular body protein 4A
Gene Symbol
CHMP4A
HGNC ID
HGNC:20274
ORF Size (aa)
798
ORF Size (bp)
798 bp
RefSeq ID
NM_014169
RefSeq Synonyms
NM_014169, BC113535, BC113533, BC010893,
Species
human
UniGene ID
Hs.279761

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.