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human GBA3 Adenovirus

Name 
Ad-h-GBA3
Cat No 
ADV-209702
Availability
4-5 weeks
Categories
Adenovirus, Over-Expression

This is an Adenovirus expressing Human GBA3.

ADV-209702
Ad-h-GBA3

Ready-to-use Adenovirus expressing Human GBA3 (glucosylceramidase beta 3 (gene/pseudogene)). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
CMV
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
CBG; CBGL1; GLUC; KLRP
Description (Vector)
GBA3, or cytosolic beta-glucosidase (EC 3.2.1.21), is a predominantly liver enzyme that efficiently hydrolyzes beta-D-glucoside and beta-D-galactoside, but not any known physiologic beta-glycoside, suggesting that it may be involved in detoxification of plant glycosides (de Graaf et al., 2001 (PubMed 11389701)). GBA3 also has significant neutral glycosylceramidase activity (EC 3.2.1.62), suggesting that it may be involved in a nonlysosomal catabolic pathway of glucosylceramide metabolism (Hayashi et al., 2007 (PubMed 17595169)).(supplied by OMIM, Mar 2008)
Gene ID
57733
Gene Name (Vector)
glucosylceramidase beta 3 (gene/pseudogene)
Gene Symbol
GBA3
HGNC ID
HGNC:19069
ORF Size (aa)
1410
ORF Size (bp)
1410 bp
RefSeq ID
NM_020973
RefSeq Synonyms
NM_020973, NM_001277225, NM_001128432, BC136264, BC101829, BC029362,
Species
human
UniGene ID
Hs.653107

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.