human CES8 Over-expression AAV

Name 
AAV-h-CES8
Cat No 
AAV-205027
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human CES4A.

AAV-205027
AAV-h-CES8

Ready-to-use AAV expressing Human CES4A (carboxylesterase 4A). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
CES6; CES8
Description (Vector)
CES4A encodes a member of the carboxylesterase large family. The family members are responsible for the hydrolysis or transesterification of various xenobiotics, such as cocaine and heroin, and endogenous substrates with ester, thioester, or amide bonds. They also participate in fatty acyl and cholesterol ester metabolism, and may play a role in the blood-brain barrier system. This gene, also called CES6, encodes a secreted enzyme, and may play a role in the detoxification of drugs and xenobiotics in neural and other tissues of the body and in the cerebrospinal fluid. Multiple transcript variants encoding different isoforms have been reported, but the full-length nature and/or biological validity of some variants have not been determined.
Gene ID
283848
Gene Name (Vector)
carboxylesterase 4A
Gene Symbol
CES4A
ORF Size (aa)
1476
ORF Size (bp)
1476 bp
RefSeq ID
NM_173815
RefSeq Synonyms
NM_173815, NM_001318506, NM_001190202, NM_001190201, BC166638,
Species
human
UniGene ID
Hs.346947

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.