mouse SRRT Adenovirus

Name 
Ad-m-SRRT
Cat No 
ADV-281128
Availability
4-5 weeks
Categories
Adenovirus, Over-Expression

This is an Adenovirus expressing Mouse Srrt.

ADV-281128
Ad-m-SRRT

Ready-to-use Adenovirus expressing Mouse Srrt (serrate RNA effector molecule homolog (Arabidopsis)). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
CMV
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
2810019G02Rik; Ars2; Asr2; ASR2A; ASR2B; ASR2C; ASR2D
Description (Vector)
Acts as a mediator between the cap-binding complex (CBC) and the primary microRNAs (miRNAs) processing machinery during cell proliferation. Contributes to the stability and delivery of capped primary miRNA transcripts to the primary miRNA processing complex containing DGCR8 and DROSHA, thereby playing a role in RNA-mediated gene silencing (RNAi) by miRNAs. Binds capped RNAs (m7GpppG-capped RNA); however interaction is probably mediated via its interaction with NCBP1/CBP80 component of the CBC complex. Involved in cell cycle progression at S phase. Does not directly confer arsenite resistance but rather modulates arsenic sensitivity. Independently of its activity on miRNAs, necessary and sufficient to promote neural stem cell self-renewal. Does so by directly binding SOX2 promoter and positively regulating its transcription (By similarity).
Gene ID
83701
Gene Name (Vector)
serrate RNA effector molecule homolog (Arabidopsis)
Gene Symbol
Srrt
ORF Size (aa)
2607
ORF Size (bp)
2607 bp
RefSeq ID
NM_031405
RefSeq Synonyms
NM_031405, NM_001109910, NM_001109909, BC066831,
Species
mouse
UniGene ID
Mm.387734

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.