mouse ZFAND5 Adenovirus
This is an Adenovirus expressing Mouse Zfand5.
ADV-277866
Ad-m-ZFAND5
Ready-to-use Adenovirus expressing Mouse Zfand5 (zinc finger, AN1-type domain 5). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
2310057A04Rik; 5830475F03Rik; AA415485; Za20d2; Zfp216
Description (Vector)
Involved in protein degradation via the ubiquitin-proteasome system. May act by anchoring ubiquitinated proteins to the proteasome. Plays a role in ubiquitin-mediated protein degradation during muscle atrophy. Plays a role in the regulation of NF-kappa-B activation and apoptosis. Inhibits NF-kappa-B activation triggered by overexpression of RIPK1 and TRAF6 but not of RELA. Inhibits also tumor necrosis factor (TNF), IL-1 and TLR4-induced NF-kappa-B activation in a dose-dependent manner. Overexpression sensitizes cells to TNF-induced apoptosis. Is a potent inhibitory factor for osteoclast differentiation.
Gene ID
22682
Gene Name (Vector)
zinc finger, AN1-type domain 5
Gene Symbol
Zfand5
ORF Size (aa)
642
RefSeq ID
NM_009551
RefSeq Synonyms
NM_009551, BC119126, BC119124, BC107566,
Species
mouse
UniGene ID
Mm.292405
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.