human CCNK Over-expression AAV
This is an AAV expressing Human CCNK.
AAV-204514
AAV-h-CCNK
Ready-to-use AAV expressing Human CCNK (cyclin K). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
CPR4; cyclin-K
Description (eCommerce)
Cyclin K is a member of the cyclin family of regulatory proteins that associate with and activate cyclin-dependent kinases (CDKs) to regulate cell cycle progression. Cyclin K can function in transcription and interacts with CDK9 to form one of multiple nuclear complexes collectively referred to as positive transcription elongation factor b (P-TEFb).
Description (Vector)
CCNK is a member of the transcription cyclin family. These cyclins may regulate transcription through their association with and activation of cyclin-dependent kinases (CDK) that phosphorylate the C-terminal domain (CTD) of the large subunit of RNA polymerase II. This gene product may play a dual role in regulating CDK and RNA polymerase II activities.
Gene ID
8812
Gene Name (eCommerce)
cyclin K
Gene Name (Vector)
cyclin K
Gene Symbol
CCNK
HGNC ID
HGNC:1596
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1065
ORF Size (bp)
1065 bp
Protein Name (eCommerce)
Cyclin-K
RefSeq ID
NM_001099402
RefSeq Synonyms
NM_001099402, BC015935,
Research Areas
Cell Cycle,Cell Division,Transcription Factor/Regulator
Research Areas (Faceted)
cell_biology,cell_cycle,genetics,transcription_translation
Species
human
Target Sentence
Cyclin K is a member of the cyclin family of regulatory proteins that associate with and activate cyclin-dependent kinases (CDKs) to regulate cell cycle progression. Cyclin K can function in transcription and interacts with CDK9 to form one of multiple nuclear complexes collectively referred to as positive transcription elongation factor b (P-TEFb).
UniGene ID
Hs.510409
UniProt ID (eCommerce)
O75909
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.