mouse THBD Adenovirus

Name 
Ad-m-THBD
Cat No 
ADV-274144
Availability
4-5 weeks
Categories
Adenovirus, Over-Expression

This is an Adenovirus expressing Mouse Thbd.

ADV-274144
Ad-m-THBD

Ready-to-use Adenovirus expressing Mouse Thbd (thrombomodulin). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
CMV
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
AI385582; CD antigen CD141; CD141; fetomodulin; snoRNA MBII-339; thrombomodulin; TM
Description (eCommerce)
Thrombomodulin is a specific endothelial cell receptor that forms a 1:1 stoichiometric complex with thrombin. This complex is responsible for the conversion of protein C to the activated protein C (protein Ca). Once evolved, protein Ca scissions the activated cofactors of the coagulation mechanism, factor Va and factor VIIIa, and thereby reduces the amount of thrombin generated. [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/P07204].
Description (Vector)
Thrombomodulin is a specific endothelial cell receptor that forms a 1:1 stoichiometric complex with thrombin. This complex is responsible for the conversion of protein C to the activated protein C (protein Ca). Once evolved, protein Ca scissions the activated cofactors of the coagulation mechanism, factor Va and factor VIIIa, and thereby reduces the amount of thrombin generated.
Gene ID
21824
Gene Name (eCommerce)
thrombomodulin
Gene Name (Vector)
thrombomodulin
Gene Symbol
Thbd
NCBI Taxonomy ID (eCommerce)
10090.0
ORF Size (aa)
1734
ORF Size (bp)
1734 bp
Protein Name (eCommerce)
Thrombomodulin
RefSeq ID
NM_009378
RefSeq Synonyms
NM_009378, BC019154,
Research Areas
Cardiovascular,Immunology,Signal Transduction
Research Areas (Faceted)
cardiovascular,immunology,signal_transduction
Species
mouse
Target Sentence
Thrombomodulin is a specific endothelial cell receptor that forms a 1:1 stoichiometric complex with thrombin. This complex is responsible for the conversion of protein C to the activated protein C (protein Ca). Once evolved, protein Ca scissions the activated cofactors of the coagulation mechanism, factor Va and factor VIIIa, and thereby reduces the amount of thrombin generated. [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/P07204].
UniGene ID
Mm.24096
UniProt ID (eCommerce)
P15306

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.