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human CCDC6 Over-expression AAV

Name 
AAV-h-CCDC6
Cat No 
AAV-204342
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human CCDC6.

AAV-204342
AAV-h-CCDC6

Ready-to-use AAV expressing Human CCDC6 (coiled-coil domain containing 6). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
coiled-coil domain-containing protein 6; D10S170; H4; papillary thyroid carcinoma-encoded protein; Protein H4; PTC; TPC; TST1
Description (eCommerce)
CCDC6 is the product of the H4(D10S170) gene identified as a gene that exhibits frequent rearrangement with RET in papillary thyroid tumors.
Description (Vector)
CCDC6 encodes a coiled-coil domain-containing protein. The encoded protein is ubiquitously expressed and may function as a tumor suppressor. A chromosomal rearrangement resulting in the expression of a fusion gene containing a portion of this gene and the intracellular kinase-encoding domain of the ret proto-oncogene is the cause of thyroid papillary carcinoma.
Gene ID
8030
Gene Name (eCommerce)
coiled-coil domain containing 6
Gene Name (Vector)
coiled-coil domain containing 6
Gene Symbol
CCDC6
HGNC ID
HGNC:18782
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1425
ORF Size (bp)
1425 bp
Protein Name (eCommerce)
Coiled-coil domain-containing protein 6
RefSeq ID
NM_005436
RefSeq Synonyms
NM_005436, BC064391, BC036757,
Research Areas
Cancer,Cytoskeleton,DNA Damage/Repair
Research Areas (Faceted)
cancer,cell_biology,genetics,transcription_translation
Species
human
Target Sentence
CCDC6 is the product of the H4(D10S170) gene identified as a gene that exhibits frequent rearrangement with RET in papillary thyroid tumors.
UniGene ID
Hs.591360
UniProt ID (eCommerce)
Q16204

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.